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Computational Modelling of Genome-Side Transcription Assembly Networks Using a Fluidics Analogy

Understanding how a myriad of transcription regulators work to modulate mRNA output at thousands of genes remains a fundamental challenge in molecular biology. Here we develop a computational tool to aid in assessing the plausibility of gene regulatory models derived from genome-wide expression prof...

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Detalles Bibliográficos
Autores principales: Azmy, Yousry Y., Gupta, Anshuman, Pugh, B. Franklin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518210/
https://www.ncbi.nlm.nih.gov/pubmed/18769485
http://dx.doi.org/10.1371/journal.pone.0003095