Trogocytosis of MHC-I/Peptide Complexes Derived from Tumors and Infected Cells Enhances Dendritic Cell Cross-Priming and Promotes Adaptive T Cell Responses

The transporter associated with antigen processing (TAP) and the major histocompatibility complex class I (MHC-I), two important components of the MHC-I antigen presentation pathway, are often deficient in tumor cells. The restoration of their expression has been shown to restore the antigenicity an...

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Detalles Bibliográficos
Autores principales: Zhang, Qian-Jin, Li, Xiao-Lin, Wang, David, Huang, Xiao-Cong, Mathis, J. Michael, Duan, Wei-Ming, Knight, David, Shi, Runhua, Glass, Jonathan, Zhang, Dong-Qing, Eisenbach, Lea, Jefferies, Wilfred A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518214/
https://www.ncbi.nlm.nih.gov/pubmed/18769733
http://dx.doi.org/10.1371/journal.pone.0003097

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