Cargando…

Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease

BACKGROUND: Alzheimer's disease (AD) is a progressive, neurodegenerative disease mostly affecting the basal forebrain, cortex and hippocampus whereas the cerebellum is relatively spared. The reason behind this region-specific brain damage in AD is not well understood. Here, we report our data s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patil, Sachin, Balu, Deebika, Melrose, Joseph, Chan, Christina
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518273/ https://www.ncbi.nlm.nih.gov/pubmed/18710535 http://dx.doi.org/10.1186/1756-0500-1-20

Ejemplares similares

Oxidative modification of lipoic acid by HNE in Alzheimer disease brain()
por: Hardas, Sarita S., et al.
Publicado: (2013)

Cytotoxicity and Genotoxicity Assessment of Ascorbyl Palmitate (AP) Food Additive
por: Sohrabi, Yousef, et al.
Publicado: (2018)

APOE genotype and sex modulate Alzheimer’s disease pathology in aged EFAD transgenic mice
por: Balu, Deebika, et al.
Publicado: (2023)

Tetrahydroxy stilbene glucoside alleviates palmitic acid-induced inflammation and apoptosis in cardiomyocytes by regulating miR-129-3p/Smad3 signaling
por: ZOU, Yong, et al.
Publicado: (2019)

Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease
por: Jahn, Thomas R., et al.
Publicado: (2011)

Stress-induced decreases in local cerebral glucose utilization in specific regions of the mouse brain
por: Warnock, Geoff I, et al.
Publicado: (2011)

Effect of cis- and trans-Monounsaturated Fatty Acids on Palmitate Toxicity and on Palmitate-induced Accumulation of Ceramides and Diglycerides
por: Sarnyai, Farkas, et al.
Publicado: (2020)

Inhibition of ACAT as a Therapeutic Target for Alzheimer’s Disease Is Independent of ApoE4 Lipidation
por: Valencia-Olvera, Ana C., et al.
Publicado: (2023)

Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes
por: Yang, Ming, et al.
Publicado: (2013)

Brain-Region Specific Metabolic Abnormalities in Parkinson’s Disease and Levodopa-Induced Dyskinesia
por: Yang, Changwei, et al.
Publicado: (2020)

Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12
por: Cheon, Hyae Gyeong, et al.
Publicado: (2014)

Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon
por: Collins, S. C., et al.
Publicado: (2008)

Effects of ethanol on immune response in the brain: region-specific changes in aged mice
por: Kane, Cynthia JM, et al.
Publicado: (2013)

Voxel-based Specific Regional Analysis System for Alzheimer’s Disease (VSRAD) on 3-tesla Normal Database: Diagnostic Accuracy in Two Independent Cohorts with Early Alzheimer’s Disease
por: Sone, Daichi, et al.
Publicado: (2018)

Ceramide and palmitic acid inhibit macrophage-mediated epithelial–mesenchymal transition in colorectal cancer
por: de Araujo Junior, Raimundo Fernandes, et al.
Publicado: (2020)

Brain region-specific genome-wide deoxyribonucleic acid methylation analysis in patients with Alzheimer’s disease
por: Ren, Gang, et al.
Publicado: (2023)

Impact of Dietary Palmitic Acid on Lipid Metabolism
por: Murru, Elisabetta, et al.
Publicado: (2022)

Metabolomic Signatures of Alzheimer’s Disease Indicate Brain Region-Specific Neurodegenerative Progression
por: Ambeskovic, Mirela, et al.
Publicado: (2023)

Regional Comparison of Imaging Biomarkers in the Striatum between Early- and Late-onset Alzheimer’s Disease
por: Kim, Ji Eun, et al.
Publicado: (2022)

Histopathological Patterns and Characteristics of Abnormal Cervical Smear in Madinah Region of Saudi Arabia
por: Yousif, Hala Mohammed, et al.
Publicado: (2019)

Repression of PKR Mediates Palmitate-Induced Apoptosis in HepG2 Cells through Bcl-2
por: Yang, Xuerui, et al.
Publicado: (2009)

Palmitic Acid: Physiological Role, Metabolism and Nutritional Implications
por: Carta, Gianfranca, et al.
Publicado: (2017)

The Association Between Serum Palmitic Acid and Thyroid Function
por: Zhou, Guowei, et al.
Publicado: (2022)

Self-Assembly of Palmitic Acid in the Presence of Choline Hydroxide
por: Xu, Huifang, et al.
Publicado: (2023)

Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells
por: Zhang, Yong, et al.
Publicado: (2012)

Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells
por: Khan, Muhammad Jadoon, et al.
Publicado: (2012)

Docosahexaenoic Acid Protects Muscle Cells from Palmitate-Induced Atrophy
por: Bryner, Randall W., et al.
Publicado: (2012)

Autophagy Protects against Palmitic Acid-Induced Apoptosis in Podocytes in vitro
por: Jiang, Xu-shun, et al.
Publicado: (2017)

IGF‑1 inhibits palmitic acid‑induced mitochondrial apoptosis in macrophages
por: Tang, Wanying, et al.
Publicado: (2023)

Linoleic Acid Induced Changes in SZ95 Sebocytes—Comparison with Palmitic Acid and Arachidonic Acid
por: Kovács, Dóra, et al.
Publicado: (2023)

Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids
por: Urso, C.J., et al.
Publicado: (2021)

Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease
por: Pickett, Eleanor K., et al.
Publicado: (2018)

SAT-593 Sex-Specific Modifications in MicroRNAs Contained in Exosomes of Astrocytes in Response to Palmitic Acid
por: Chowen, Julie Ann, et al.
Publicado: (2020)

Palmitic Acid-Enriched Diet Increases α-Synuclein and Tyrosine Hydroxylase Expression Levels in the Mouse Brain
por: Schommer, Jared, et al.
Publicado: (2018)

Alteration of brain function and systemic inflammatory tone in older adults by decreasing the dietary palmitic acid intake
por: Dumas, Julie A., et al.
Publicado: (2023)

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

Methodological challenges in indirect treatment comparisons: spotlight on a recent comparison of long-acting injectable aripiprazole versus paliperidone palmitate in the treatment of schizophrenia
por: Singh, Arun, et al.
Publicado: (2018)

Uncoupling Protein 2 Regulates Palmitic Acid-Induced Hepatoma Cell Autophagy
por: Lou, Jiaxin, et al.
Publicado: (2014)

Palmitic Acid Induces Müller Cell Inflammation that is Potentiated by Co-treatment with Glucose
por: Capozzi, Megan E., et al.
Publicado: (2018)

Rosiglitazone ameliorates palmitic acid-induced cytotoxicity in TM4 Sertoli cells
por: Ge, Xie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5aech62lbq2f0t57lt95i2sj2k