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RNase footprinting demonstrates antigenomic hepatitis delta virus ribozyme structural rearrangement as a result of self-cleavage reaction

BACKGROUND: Hepatitis delta virus (HDV) is a satellite virus of hepatitis B. During viral replication the 1700-nucleotide-long genomic RNA and its complement, the antigenomic RNA, undergo self-cleavage catalyzed by internal ribozyme motifs that are essential for propagation of the virus in vivo. The...

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Detalles Bibliográficos
Autores principales: Savochkina, Larissa, Alekseenkova, Victoria, Belyanko, Tatyana, Dobrynina, Nadezhda, Beabealashvilli, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518280/
https://www.ncbi.nlm.nih.gov/pubmed/18710542
http://dx.doi.org/10.1186/1756-0500-1-15

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