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A New Luminescence Assay for Autoantibodies to Mammalian Cell–Prepared Insulinoma-Associated Protein 2
OBJECTIVE—Insulinoma-associated protein 2 (IA-2) is a major autoantigen in type 1 diabetes, and IA-2 autoantibodies are routinely detected by a liquid-phase radioimmunoprecipitation assay. The present experiments were initiated to develop a new assay that does not require the use of radioisotopes or...
Autores principales: | Burbelo, Peter D., Hirai, Hiroki, Leahy, Hannah, Lernmark, Ake, Ivarsson, Sten A., Iadarola, Michael J., Louis Notkins, Abner |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518352/ https://www.ncbi.nlm.nih.gov/pubmed/18535195 http://dx.doi.org/10.2337/dc08-0286 |
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