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Pyruvate Dehydrogenase Kinase 4: Regulation by Thiazolidinediones and Implication in Glyceroneogenesis in Adipose Tissue

OBJECTIVE—Pyruvate dehydrogenase complex (PDC) serves as the metabolic switch between glucose and fatty acid utilization. PDC activity is inhibited by PDC kinase (PDK). PDC shares the same substrate, i.e., pyruvate, as glyceroneogenesis, a pathway controlling fatty acid release from white adipose ti...

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Detalles Bibliográficos
Autores principales:	Cadoudal, Thomas, Distel, Emilie, Durant, Sylvie, Fouque, Françoise, Blouin, Jean-Marc, Collinet, Martine, Bortoli, Sylvie, Forest, Claude, Benelli, Chantal
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518477/ https://www.ncbi.nlm.nih.gov/pubmed/18519799 http://dx.doi.org/10.2337/db08-0477

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