Cargando…

Deletion of Cd39/Entpd1 Results in Hepatic Insulin Resistance

OBJECTIVE—Extracellular nucleotides are important mediators of inflammatory responses and could also impact metabolic homeostasis. Type 2 purinergic (P2) receptors bind extracellular nucleotides and are expressed by major peripheral tissues responsible for glucose homeostasis. CD39/ENTPD1 is the dom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Enjyoji, Keiichi, Kotani, Ko, Thukral, Chandrashekar, Blumel, Benjamin, Sun, Xiaofeng, Wu, Yan, Imai, Masato, Friedman, David, Csizmadia, Eva, Bleibel, Wissam, Kahn, Barbara B., Robson, Simon C.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518482/ https://www.ncbi.nlm.nih.gov/pubmed/18567823 http://dx.doi.org/10.2337/db07-1265

Ejemplares similares

Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice
por: De Giorgi, Marco, et al.
Publicado: (2017)

Functional ENTPD1 Polymorphisms in African Americans With Diabetes and End-Stage Renal Disease
por: Friedman, David J., et al.
Publicado: (2009)

The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis
por: Peng, Zhen‐Wei, et al.
Publicado: (2017)

Limited TCR repertoire and ENTPD1 dysregulation mark late-stage COVID-19
por: Wang, Na, et al.
Publicado: (2021)

Glycoengineered anti-CD39 promotes anticancer responses by depleting suppressive cells and inhibiting angiogenesis in tumor models
por: Zhang, Haohai, et al.
Publicado: (2022)

Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord
por: McCoy, Eric, et al.
Publicado: (2014)

Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity
por: Jorgensen, Sebastian Beck, et al.
Publicado: (2013)

Heterozygous SOD2 Deletion Impairs Glucose-Stimulated Insulin Secretion, but Not Insulin Action, in High-Fat–Fed Mice
por: Kang, Li, et al.
Publicado: (2014)

Insulin Augmentation of Glucose-Stimulated Insulin Secretion Is Impaired in Insulin-Resistant Humans
por: Halperin, Florencia, et al.
Publicado: (2012)

Comments on Cui Q‐Q et al: “Hippocampal CD 39/ENTPD 1 promotes mouse depression‐like behavior …”
por: Zimmermann, Herbert
Publicado: (2020)

ENTPD1/CD39 as a predictive marker of treatment response to gemogenovatucel-T as maintenance therapy in newly diagnosed ovarian cancer
por: Rocconi, Rodney P., et al.
Publicado: (2022)

Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance
por: Xu, Elaine, et al.
Publicado: (2012)

Macrophage Deletion of SOCS1 Increases Sensitivity to LPS and Palmitic Acid and Results in Systemic Inflammation and Hepatic Insulin Resistance
por: Sachithanandan, Nirupa, et al.
Publicado: (2011)

Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ERα/HGF/Met Pathway
por: Zhang, Yu-Yao, et al.
Publicado: (2017)

Author Correction: ENTPD1/CD39 as a predictive marker of treatment response to gemogenovatucel-T as maintenance therapy in newly diagnosed ovarian cancer
por: Rocconi, Rodney P., et al.
Publicado: (2023)

Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism
por: Li, Mengyao, et al.
Publicado: (2015)

Association of the ENPP1/ENTPD1 Polymorphisms in Hemodialysis Patients
por: Zhang, Xi, et al.
Publicado: (2021)

Hematopoietic Cell–Restricted Deletion of CD36 Reduces High-Fat Diet–Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue
por: Nicholls, Hayley T., et al.
Publicado: (2011)

Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance
por: Vazirani, Reema P., et al.
Publicado: (2016)

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
por: Chiu, David Kung-Chun, et al.
Publicado: (2017)

Increased Hepatic Glucose Production in Fetal Sheep With Intrauterine Growth Restriction Is Not Suppressed by Insulin
por: Thorn, Stephanie R., et al.
Publicado: (2013)

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function
por: Boucher, Jeremie, et al.
Publicado: (2016)

OR12-04 LEAP2 Deletion Does Not Counteract The Effects Of Ghrelin Deletion During Insulin-Induced-Hypoglycemia
por: Shankar, Kripa, et al.
Publicado: (2023)

Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans
por: Tong, Jenny, et al.
Publicado: (2010)

Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD
por: Softic, Samir, et al.
Publicado: (2016)

Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress
por: Delibegovic, Mirela, et al.
Publicado: (2009)

Identification of ENTPD8 and cytidine in pancreatic cancer by metabolomic and transcriptomic conjoint analysis
por: An, Yong, et al.
Publicado: (2018)

Identifying small molecule probes of ENTPD5 through high throughput screening
por: Durst, Matthew A., et al.
Publicado: (2019)

Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice
por: Zemany, Laura, et al.
Publicado: (2015)

Stomach Ulcer as a Rare Cause of Pancreatitis: An Unusual Complication of a Displaced Percutaneous Endoscopic Gastrostomy Tube
por: Saleem, Saad, et al.
Publicado: (2018)

Betel Chewing and Nonalcoholic Steatohepatitis
por: Bleibel, Wissam, et al.
Publicado: (2018)

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
por: Deaglio, Silvia, et al.
Publicado: (2007)

Diurnal Pattern to Insulin Secretion and Insulin Action in Healthy Individuals
por: Saad, Ahmed, et al.
Publicado: (2012)

Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin
por: Asare-Bediako, Isaac, et al.
Publicado: (2018)

Intraperitoneal insulin administration in pigs: effect on circulating insulin and glucose levels
por: Dirnena-Fusini, Ilze, et al.
Publicado: (2021)

Enzamin ameliorates adipose tissue inflammation with impaired adipocytokine expression and insulin resistance in db/db mice
por: Tamura, Yukinori, et al.
Publicado: (2013)

Pulsatile Portal Vein Insulin Delivery Enhances Hepatic Insulin Action and Signaling
por: Matveyenko, Aleksey V., et al.
Publicado: (2012)

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion
por: Robson-Doucette, Christine A., et al.
Publicado: (2011)

Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity
por: Lee, Jong Han, et al.
Publicado: (2016)

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance
por: Kawano, Yoshinaga, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_b905n12k5vtq2cl2iip4qm24a7