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Impact of Diabetes Susceptibility Loci on Progression From Pre-Diabetes to Diabetes in At-Risk Individuals of the Diabetes Prevention Trial–Type 1 (DPT-1)

OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps: defective immunological tolerance, priming of anti-islet autoimmunity, and destruction of insulin-producing β-cells. A number of genetic loci contribute to susceptibility to type 1 diabetes, but it is unclear which stages of the...

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Detalles Bibliográficos
Autores principales:	Butty, Vincent, Campbell, Christopher, Mathis, Diane, Benoist, Christophe
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518486/ https://www.ncbi.nlm.nih.gov/pubmed/18556337 http://dx.doi.org/10.2337/db07-1736

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