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Exendin-4 Stimulation of Cyclin A2 in β-Cell Proliferation

OBJECTIVE—β-Cell proliferation is an important mechanism underlying β-cell mass adaptation to metabolic demands. We have examined effects, in particular those mediated through intracellular cAMP signaling, of the incretin hormone analog exendin-4 on cell cycle regulation in β-cells. RESEARCH DESIGN...

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Detalles Bibliográficos
Autores principales: Song, Woo-Jin, Schreiber, Weston E., Zhong, Enhong, Liu, Fei-Fei, Kornfeld, Benjamin D., Wondisford, Fredric E., Hussain, Mehboob A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518488/
https://www.ncbi.nlm.nih.gov/pubmed/18544709
http://dx.doi.org/10.2337/db07-1541