Cargando…

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes

OBJECTIVE—Activation of the receptor for advanced glycation end products (RAGE) in diabetic vasculature is considered to be a key mediator of atherogenesis. This study examines the effects of deletion of RAGE on the development of atherosclerosis in the diabetic apoE(−/−) model of accelerated athero...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soro-Paavonen, Aino, Watson, Anna M.D., Li, Jiaze, Paavonen, Karri, Koitka, Audrey, Calkin, Anna C., Barit, David, Coughlan, Melinda T., Drew, Brian G., Lancaster, Graeme I., Thomas, Merlin, Forbes, Josephine M., Nawroth, Peter P., Bierhaus, Angelika, Cooper, Mark E., Jandeleit-Dahm, Karin A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518498/ https://www.ncbi.nlm.nih.gov/pubmed/18511846 http://dx.doi.org/10.2337/db07-1808

Ejemplares similares

Alagebrium Reduces Glomerular Fibrogenesis and Inflammation Beyond Preventing RAGE Activation in Diabetic Apolipoprotein E Knockout Mice
por: Watson, Anna M.D., et al.
Publicado: (2012)

miR-200a Prevents Renal Fibrogenesis Through Repression of TGF-β2 Expression
por: Wang, Bo, et al.
Publicado: (2011)

Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse
por: Chew, Phyllis, et al.
Publicado: (2010)

Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity
por: Teismann, Peter, et al.
Publicado: (2012)

RAGE and Modulation of Ischemic Injury in the Diabetic Myocardium
por: Bucciarelli, Loredana G., et al.
Publicado: (2008)

E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor-β
por: Wang, Bo, et al.
Publicado: (2010)

Higher Plasma Soluble Receptor for Advanced Glycation End Products (sRAGE) Levels Are Associated With Incident Cardiovascular Disease and All-Cause Mortality in Type 1 Diabetes: A 12-Year Follow-Up Study
por: Nin, Johanna W.M., et al.
Publicado: (2010)

RAGE Deficiency Improves Postinjury Sciatic Nerve Regeneration in Type 1 Diabetic Mice
por: Juranek, Judyta K., et al.
Publicado: (2013)

Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes
por: Humpert, Per M, et al.
Publicado: (2007)

Glycated Hemoglobin and the Risk of Kidney Disease and Retinopathy in Adults With and Without Diabetes
por: Selvin, Elizabeth, et al.
Publicado: (2011)

The Complexity of Sporadic Alzheimer's Disease Pathogenesis: The Role of RAGE as Therapeutic Target to Promote Neuroprotection by Inhibiting Neurovascular Dysfunction
por: Perrone, Lorena, et al.
Publicado: (2012)

ApoE Polymorphism Is Associated With C-Reactive Protein in Low-HDL Family Members and in Normolipidemic Subjects
por: Kahri, Juhani, et al.
Publicado: (2006)

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia
por: Achouiti, Ahmed, et al.
Publicado: (2016)

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes
por: Rabbani, Naila, et al.
Publicado: (2011)

Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse
por: Reiniger, Nina, et al.
Publicado: (2010)

Insulin exposure mitigates the increase of arterial stiffness in patients with type 2 diabetes and albuminuria: an exploratory analysis
por: Gordin, Daniel, et al.
Publicado: (2019)

Relationship of Glycated Albumin to Blood Glucose and HbA(1c) Values and to Retinopathy, Nephropathy, and Cardiovascular Outcomes in the DCCT/EDIC Study
por: Nathan, David M., et al.
Publicado: (2014)

Skin Advanced Glycation End Products Glucosepane and Methylglyoxal Hydroimidazolone Are Independently Associated With Long-term Microvascular Complication Progression of Type 1 Diabetes
por: Genuth, Saul, et al.
Publicado: (2015)

Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes
por: Saulnier, Pierre-Jean, et al.
Publicado: (2016)

Regulation of osteoclast function and bone mass by RAGE
por: Zhou, Zheng, et al.
Publicado: (2006)

Total Soluble and Endogenous Secretory Receptor for Advanced Glycation End Products as Predictive Biomarkers of Coronary Heart Disease Risk in Patients With Type 2 Diabetes: An Analysis From the CARDS Trial
por: Colhoun, Helen M., et al.
Publicado: (2011)

Levels of Oxidized LDL and Advanced Glycation End Products–Modified LDL in Circulating Immune Complexes Are Strongly Associated With Increased Levels of Carotid Intima-Media Thickness and Its Progression in Type 1 Diabetes
por: Lopes-Virella, Maria F., et al.
Publicado: (2011)

Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis
por: Bopp, Christian, et al.
Publicado: (2008)

Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice
por: McVicar, Carmel M., et al.
Publicado: (2015)

Glycation by glyoxal leads to profound changes in the behavior of dermal fibroblasts
por: Guillon, Cécile, et al.
Publicado: (2021)

Sevelamer reduces endothelial inflammatory response to advanced glycation end products
por: Gregório, Paulo C, et al.
Publicado: (2018)

The Receptor for Advanced Glycation End-products (RAGE) Sustains Autophagy and Limits Apoptosis, Promoting Pancreatic Tumor Cell Survival
por: Kang, Rui, et al.
Publicado: (2009)

RAGE signaling sustains inflammation and promotes tumor development
por: Gebhardt, Christoffer, et al.
Publicado: (2008)

Osteoprotegerin Is an Independent Predictor of Vascular Events in Finnish Adults With Type 1 Diabetes
por: Gordin, Daniel, et al.
Publicado: (2013)

RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner
por: Frommhold, David, et al.
Publicado: (2011)

Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor-β: A Model for Diabetic Podocytopathy
por: Herman-Edelstein, Michal, et al.
Publicado: (2011)

The Impact of Salsalate Treatment on Serum Levels of Advanced Glycation End Products in Type 2 Diabetes
por: Barzilay, Joshua I., et al.
Publicado: (2014)

Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy
por: Thallas‐Bonke, Vicki, et al.
Publicado: (2014)

Plasma advanced glycation end products and the subsequent risk of microvascular complications in type 1 diabetes in the DCCT/EDIC
por: Monnier, Vincent M, et al.
Publicado: (2022)

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function
por: Miller, Antonia G., et al.
Publicado: (2010)

Foxo1 Inhibits Diabetic Mucosal Wound Healing but Enhances Healing of Normoglycemic Wounds
por: Xu, Fanxing, et al.
Publicado: (2015)

Evidence That Hyperglycemia After Recovery From Hypoglycemia Worsens Endothelial Function and Increases Oxidative Stress and Inflammation in Healthy Control Subjects and Subjects With Type 1 Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2012)

Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation
por: Riehl, Astrid, et al.
Publicado: (2010)

A Novel Cellular Defect in Diabetes: Membrane Repair Failure
por: Howard, Amber C., et al.
Publicado: (2011)

Cumulative Risk, Age at Onset, and Sex-Specific Differences for Developing End-Stage Renal Disease in Young Patients With Type 1 Diabetes: A Nationwide Population-Based Cohort Study
por: Möllsten, Anna, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_pd5b94smbvggphgkoq68s3tcj9