Differential Roles of Cardiomyocyte and Macrophage Peroxisome Proliferator–Activated Receptor γ in Cardiac Fibrosis

OBJECTIVE—Cardiac fibrosis is an important component of diabetic cardiomyopathy. Peroxisome proliferator–activated receptor γ (PPARγ) ligands repress proinflammatory gene expression, including that of osteopontin, a known contributor to the development of myocardial fibrosis. We thus investigated th...

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Detalles Bibliográficos
Autores principales: Caglayan, Evren, Stauber, Bradley, Collins, Alan R., Lyon, Christopher J., Yin, Fen, Liu, Joey, Rosenkranz, Stephan, Erdmann, Erland, Peterson, Leif E., Ross, Robert S., Tangirala, Rajendra K., Hsueh, Willa A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518499/
https://www.ncbi.nlm.nih.gov/pubmed/18511847
http://dx.doi.org/10.2337/db07-0924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518499/
https://www.ncbi.nlm.nih.gov/pubmed/18511847
http://dx.doi.org/10.2337/db07-0924

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