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Differential Roles of Cardiomyocyte and Macrophage Peroxisome Proliferator–Activated Receptor γ in Cardiac Fibrosis
OBJECTIVE—Cardiac fibrosis is an important component of diabetic cardiomyopathy. Peroxisome proliferator–activated receptor γ (PPARγ) ligands repress proinflammatory gene expression, including that of osteopontin, a known contributor to the development of myocardial fibrosis. We thus investigated th...
Autores principales: | Caglayan, Evren, Stauber, Bradley, Collins, Alan R., Lyon, Christopher J., Yin, Fen, Liu, Joey, Rosenkranz, Stephan, Erdmann, Erland, Peterson, Leif E., Ross, Robert S., Tangirala, Rajendra K., Hsueh, Willa A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518499/ https://www.ncbi.nlm.nih.gov/pubmed/18511847 http://dx.doi.org/10.2337/db07-0924 |
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