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Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes
OBJECTIVE— We evaluated the impact on diabetes-related intermediary traits of common novel type 2 diabetes–associated variants in the JAZF1 (rs864745), CDC123/CAMK1D (rs12779790), TSPAN8 (rs7961581), THADA (rs7578597), ADAMTS9 (rs4607103), and NOTCH2 (rs10923931) loci, which were recently identified...
Autores principales: | Grarup, Niels, Andersen, Gitte, Krarup, Nikolaj T., Albrechtsen, Anders, Schmitz, Ole, Jørgensen, Torben, Borch-Johnsen, Knut, Hansen, Torben, Pedersen, Oluf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518507/ https://www.ncbi.nlm.nih.gov/pubmed/18567820 http://dx.doi.org/10.2337/db08-0436 |
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