Self-eating from an ER-associated cup

Since the first morphological description of autophagosomes in the early 1960s, two critical questions have been a matter of intense investigation and debate: what is the origin of the autophagosomal membrane and how is it formed? A study by Axe et al. (E.L. Axe, S.A. Walker, M. Manifava, P. Chandra...

Descripción completa

Detalles Bibliográficos
Autores principales: Simonsen, Anne, Stenmark, Harald
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518700/
https://www.ncbi.nlm.nih.gov/pubmed/18725534
http://dx.doi.org/10.1083/jcb.200807061
_version_ 1782158597372772352
author Simonsen, Anne
Stenmark, Harald
author_facet Simonsen, Anne
Stenmark, Harald
author_sort Simonsen, Anne
collection PubMed
description Since the first morphological description of autophagosomes in the early 1960s, two critical questions have been a matter of intense investigation and debate: what is the origin of the autophagosomal membrane and how is it formed? A study by Axe et al. (E.L. Axe, S.A. Walker, M. Manifava, P. Chandra, H.L. Roderick, A. Habermann, G. Griffiths, and N.T. Ktistakis. 2008. J. Cell Biol. 182:685–701) provides evidence that cup-shaped protrusions from the endoplasmic reticulum, named omegasomes, serve as platforms for autophagosome biogenesis in mammalian cells.
format Text
id pubmed-2518700
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-25187002009-02-25 Self-eating from an ER-associated cup Simonsen, Anne Stenmark, Harald J Cell Biol Reviews Since the first morphological description of autophagosomes in the early 1960s, two critical questions have been a matter of intense investigation and debate: what is the origin of the autophagosomal membrane and how is it formed? A study by Axe et al. (E.L. Axe, S.A. Walker, M. Manifava, P. Chandra, H.L. Roderick, A. Habermann, G. Griffiths, and N.T. Ktistakis. 2008. J. Cell Biol. 182:685–701) provides evidence that cup-shaped protrusions from the endoplasmic reticulum, named omegasomes, serve as platforms for autophagosome biogenesis in mammalian cells. The Rockefeller University Press 2008-08-25 /pmc/articles/PMC2518700/ /pubmed/18725534 http://dx.doi.org/10.1083/jcb.200807061 Text en © 2008 Simonsen and Stenmark This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Simonsen, Anne
Stenmark, Harald
Self-eating from an ER-associated cup
title Self-eating from an ER-associated cup
title_full Self-eating from an ER-associated cup
title_fullStr Self-eating from an ER-associated cup
title_full_unstemmed Self-eating from an ER-associated cup
title_short Self-eating from an ER-associated cup
title_sort self-eating from an er-associated cup
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518700/
https://www.ncbi.nlm.nih.gov/pubmed/18725534
http://dx.doi.org/10.1083/jcb.200807061
work_keys_str_mv AT simonsenanne selfeatingfromanerassociatedcup
AT stenmarkharald selfeatingfromanerassociatedcup

Ejemplares similares