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Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments

The actin-related protein 2/3 (Arp2/3) complex is the primary nucleator of new actin filaments in most crawling cells. Nucleation-promoting factors (NPFs) of the Wiskott-Aldrich syndrome protein (WASP)/Scar family are the currently recognized activators of the Arp2/3 complex. We now report that the...

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Detalles Bibliográficos
Autores principales:	LeClaire, Lawrence L., Baumgartner, Martin, Iwasa, Janet H., Mullins, R. Dyche, Barber, Diane L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518704/ https://www.ncbi.nlm.nih.gov/pubmed/18725535 http://dx.doi.org/10.1083/jcb.200802145

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