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Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
Autophagy is the engulfment of cytosol and organelles by double-membrane vesicles termed autophagosomes. Autophagosome formation is known to require phosphatidylinositol 3-phosphate (PI(3)P) and occurs near the endoplasmic reticulum (ER), but the exact mechanisms are unknown. We show that double FYV...
Autores principales: | Axe, Elizabeth L., Walker, Simon A., Manifava, Maria, Chandra, Priya, Roderick, H. Llewelyn, Habermann, Anja, Griffiths, Gareth, Ktistakis, Nicholas T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518708/ https://www.ncbi.nlm.nih.gov/pubmed/18725538 http://dx.doi.org/10.1083/jcb.200803137 |
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