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Poleward transport of Eg5 by dynein–dynactin in Xenopus laevis egg extract spindles
Molecular motors are required for spindle assembly and maintenance during cell division. How motors move and interact inside spindles is unknown. Using photoactivation and photobleaching, we measure mitotic motor movement inside a dynamic spindle. We find that dynein–dynactin transports the essentia...
Autores principales: | Uteng, Marianne, Hentrich, Christian, Miura, Kota, Bieling, Peter, Surrey, Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518710/ https://www.ncbi.nlm.nih.gov/pubmed/18710923 http://dx.doi.org/10.1083/jcb.200801125 |
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