Glucose and GLP-1 Stimulate cAMP Production via Distinct Adenylyl Cyclases in INS-1E Insulinoma Cells

In β cells, both glucose and hormones, such as GLP-1, stimulate production of the second messenger cAMP, but glucose and GLP-1 elicit distinct cellular responses. We now show in INS-1E insulinoma cells that glucose and GLP-1 produce cAMP with distinct kinetics via different adenylyl cyclases. GLP-1...

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Detalles Bibliográficos
Autores principales: Ramos, Lavoisier S., Zippin, Jonathan Hale, Kamenetsky, Margarita, Buck, Jochen, Levin, Lonny R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518727/
https://www.ncbi.nlm.nih.gov/pubmed/18695009
http://dx.doi.org/10.1085/jgp.200810044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518727/
https://www.ncbi.nlm.nih.gov/pubmed/18695009
http://dx.doi.org/10.1085/jgp.200810044

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