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Mutations of Nonconserved Residues within the Calcium Channel α(1)-interaction Domain Inhibit β-Subunit Potentiation
Voltage-dependent calcium channels consist of a pore-forming subunit (Ca(V)α(1)) that includes all the molecular determinants of a voltage-gated channel, and several accessory subunits. The ancillary β-subunit (Ca(V)β) is a potent activator of voltage-dependent calcium channels, but the mechanisms a...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518731/ https://www.ncbi.nlm.nih.gov/pubmed/18725532 http://dx.doi.org/10.1085/jgp.200709901 |