Novel sequence variants and a high frequency of recurrent polymorphisms in BRCA1 gene in Sri Lankan breast cancer patients and at risk individuals

BACKGROUND: Breast Cancer is the most commonly diagnosed cancer among Sri Lankan women. Germline mutations in the susceptibility genes BRCA1 and BRCA2 in hereditary breast/ovarian cancer, though low in prevalence, are highly penetrant and show geographical variations. There have been only a few repo...

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Detalles Bibliográficos
Autores principales: De Silva, Wasanthi, Karunanayake, Eric H, Tennekoon, Kamani H, Allen, Marie, Amarasinghe, Indrani, Angunawala, Preethika, Ziard, Mohamed H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519088/
https://www.ncbi.nlm.nih.gov/pubmed/18662409
http://dx.doi.org/10.1186/1471-2407-8-214

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