Cyclin T1-Dependent Genes in Activated CD4(+) T and Macrophage Cell Lines Appear Enriched in HIV-1 Co-Factors

HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4(+) T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II elongation factor known as P-TEFb. Cyclin T1 is target...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Wendong, Ramakrishnan, Rajesh, Wang, Yan, Chiang, Karen, Sung, Tzu-Ling, Rice, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519787/
https://www.ncbi.nlm.nih.gov/pubmed/18773076
http://dx.doi.org/10.1371/journal.pone.0003146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519787/
https://www.ncbi.nlm.nih.gov/pubmed/18773076
http://dx.doi.org/10.1371/journal.pone.0003146

Ejemplares similares