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Cyclin T1-Dependent Genes in Activated CD4(+) T and Macrophage Cell Lines Appear Enriched in HIV-1 Co-Factors
HIV-1 is dependent upon cellular co-factors to mediate its replication cycle in CD4(+) T cells and macrophages, the two major cell types infected by the virus in vivo. One critical co-factor is Cyclin T1, a subunit of a general RNA polymerase II elongation factor known as P-TEFb. Cyclin T1 is target...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519787/ https://www.ncbi.nlm.nih.gov/pubmed/18773076 http://dx.doi.org/10.1371/journal.pone.0003146 |