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Identifying Cognate Binding Pairs among a Large Set of Paralogs: The Case of PE/PPE Proteins of Mycobacterium tuberculosis

We consider the problem of how to detect cognate pairs of proteins that bind when each belongs to a large family of paralogs. To illustrate the problem, we have undertaken a genomewide analysis of interactions of members of the PE and PPE protein families of Mycobacterium tuberculosis. Our computati...

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Detalles Bibliográficos
Autores principales:	Riley, Robert, Pellegrini, Matteo, Eisenberg, David
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519833/ https://www.ncbi.nlm.nih.gov/pubmed/18787688 http://dx.doi.org/10.1371/journal.pcbi.1000174

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