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Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127(pos) Depletion, Treg Expansion, and Treg Cryopreservation

BACKGROUND: Treg based immunotherapy is of great interest to facilitate tolerance in autoimmunity and transplantation. For clinical trials, it is essential to have a clinical grade Treg isolation protocol in accordance with Good Manufacturing Practice (GMP) guidelines. To obtain sufficient Treg for...

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Detalles Bibliográficos
Autores principales:	Peters, Jorieke H., Preijers, Frank W., Woestenenk, Rob, Hilbrands, Luuk B., Koenen, Hans J. P. M., Joosten, Irma
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2522271/ https://www.ncbi.nlm.nih.gov/pubmed/18776930 http://dx.doi.org/10.1371/journal.pone.0003161

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