Spontaneous Skin Ulceration and Defective T Cell Function in CD18 Null Mice

A null mutation was prepared in the mouse for CD18, the β(2) subunit of leukocyte integrins. Homozygous CD18 null mice develop chronic dermatitis with extensive facial and submandibular erosions. The phenotype includes elevated neutrophil counts, increased immunoglobulin levels, lymphadenopathy, spl...

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Detalles Bibliográficos
Autores principales: Scharffetter-Kochanek, Karin, Lu, Huifang, Norman, Keith, van Nood, Nicole, Munoz, Flor, Grabbe, Stephan, McArthur, Mark, Lorenzo, Isabel, Kaplan, Sheldon, Ley, Klaus, Wayne Smith, C., Montgomery, Charles A., Rich, Susan, Beaudet, Arthur L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525537/
https://www.ncbi.nlm.nih.gov/pubmed/9653089

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