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Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

Embryonic stem cells (ESCs) could potentially compensate for the lack of blood platelets available for use in transfusions. Here, we describe a new method for generating mouse ESC-derived platelets (ESPs) that can contribute to hemostasis in vivo. Flow cytometric sorting of cells from embryoid bodie...

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Detalles Bibliográficos
Autores principales:	Nishikii, Hidekazu, Eto, Koji, Tamura, Noriko, Hattori, Koichi, Heissig, Beate, Kanaji, Taisuke, Sawaguchi, Akira, Goto, Shinya, Ware, Jerry, Nakauchi, Hiromitsu
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525582/ https://www.ncbi.nlm.nih.gov/pubmed/18663123 http://dx.doi.org/10.1084/jem.20071482

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