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Continuous engagement of a self-specific activation receptor induces NK cell tolerance

Natural killer (NK) cell tolerance mechanisms are incompletely understood. One possibility is that they possess self-specific activation receptors that result in hyporesponsiveness unless modulated by self–major histocompatability complex (MHC)–specific inhibitory receptors. As putative self-specifi...

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Detalles Bibliográficos
Autores principales: Tripathy, Sandeep K., Keyel, Peter A., Yang, Liping, Pingel, Jeanette T., Cheng, Tammy P., Schneeberger, Achim, Yokoyama, Wayne M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525593/
https://www.ncbi.nlm.nih.gov/pubmed/18606857
http://dx.doi.org/10.1084/jem.20072446