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Continuous engagement of a self-specific activation receptor induces NK cell tolerance
Natural killer (NK) cell tolerance mechanisms are incompletely understood. One possibility is that they possess self-specific activation receptors that result in hyporesponsiveness unless modulated by self–major histocompatability complex (MHC)–specific inhibitory receptors. As putative self-specifi...
Autores principales: | Tripathy, Sandeep K., Keyel, Peter A., Yang, Liping, Pingel, Jeanette T., Cheng, Tammy P., Schneeberger, Achim, Yokoyama, Wayne M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525593/ https://www.ncbi.nlm.nih.gov/pubmed/18606857 http://dx.doi.org/10.1084/jem.20072446 |
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