Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression

BACKGROUND: Childhood pre-B acute lymphoblastic leukemia (ALL) is a bone marrow (BM) derived disease, which often disseminates out of the BM cavity, where malignant cells to a variable degree can be found circulating in the peripheral blood (PB). Normal pre-B cells are absolutely dependent on BM str...

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Detalles Bibliográficos
Autores principales: Hansson, Frida, Toporski, Jacek, Månsson, Robert, Johansson, Bertil, Norén-Nyström, Ulrika, Jacobsen, Sten Eirik W, Wiebe, Thomas, Larsson, Marcus, Sigvardsson, Mikael, Castor, Anders
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525657/
https://www.ncbi.nlm.nih.gov/pubmed/18694513
http://dx.doi.org/10.1186/1476-4598-7-67

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