Cargando…
Muscarinic K(+) Channel in the Heart : Modal Regulation by G Protein βγ Subunits
The membrane-delimited activation of muscarinic K(+) channels by G protein βγ subunits plays a prominent role in the inhibitory synaptic transmission in the heart. These channels are thought to be heterotetramers comprised of two homologous subunits, GIRK1 and CIR, both members of the family of inwa...
Autores principales: | Ivanova-Nikolova, Tatyana T., Nikolov, Emil N., Hansen, Carl, Robishaw, Janet D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525744/ https://www.ncbi.nlm.nih.gov/pubmed/9689027 |
Ejemplares similares
-
Effector Contributions to Gβγ-mediated Signaling as Revealed
by Muscarinic Potassium Channel Gating
por: Ivanova-Nikolova, Tatyana T., et al.
Publicado: (1997) -
Kir3 channel ontogeny – the role of Gβγ subunits in channel assembly and trafficking
por: Zylbergold, Peter, et al.
Publicado: (2014) -
Differential Localization of G Protein βγ
Subunits
por: Betke, Katherine M., et al.
Publicado: (2014) -
G protein βγ subunits inhibit TRPM3 ion channels in sensory neurons
por: Quallo, Talisia, et al.
Publicado: (2017) -
Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source
por: Shen, Jia X., et al.
Publicado: (2012)