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MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis
Two eukaryotic pathways for processing double-strand breaks (DSBs) as crossovers have been described, one dependent on the MutL homologs Mlh1 and Mlh3, and the other on the structure-specific endonuclease Mus81. Mammalian MUS81 has been implicated in maintenance of genomic stability in somatic cells...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525838/ https://www.ncbi.nlm.nih.gov/pubmed/18787696 http://dx.doi.org/10.1371/journal.pgen.1000186 |