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Protein Meta-Functional Signatures from Combining Sequence, Structure, Evolution, and Amino Acid Property Information
Protein function is mediated by different amino acid residues, both their positions and types, in a protein sequence. Some amino acids are responsible for the stability or overall shape of the protein, playing an indirect role in protein function. Others play a functionally important role as part of...
Autores principales: | Wang, Kai, Horst, Jeremy A., Cheng, Gong, Nickle, David C., Samudrala, Ram |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526173/ https://www.ncbi.nlm.nih.gov/pubmed/18818722 http://dx.doi.org/10.1371/journal.pcbi.1000181 |
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