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CD4(+)FoxP3(+) regulatory T cells confer infectious tolerance in a TGF-β–dependent manner
CD4(+)FoxP3(+) regulatory T (T reg) cells comprise a separate lineage of T cells that are essential for maintaining immunological tolerance to self. The molecular mechanism(s) by which T reg cells mediate their suppressive effects remains poorly understood. One molecule that has been extensively stu...
Autores principales: | Andersson, John, Tran, Dat Q., Pesu, Marko, Davidson, Todd S., Ramsey, Heather, O'Shea, John J., Shevach, Ethan M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526184/ https://www.ncbi.nlm.nih.gov/pubmed/18710931 http://dx.doi.org/10.1084/jem.20080308 |
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