AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

Immunoglobulin (Ig) isotype switching is a recombination event that changes the constant domain of antibody genes and is catalyzed by activation-induced cytidine deaminase (AID). Upon recruitment to Ig genes, AID deaminates cytidines at switch (S) recombination sites, leading to the formation of DNA...

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Detalles Bibliográficos
Autores principales: Takizawa, Makiko, Tolarová, Helena, Li, Zhiyu, Dubois, Wendy, Lim, Susan, Callen, Elsa, Franco, Sonia, Mosaico, Maria, Feigenbaum, Lionel, Alt, Frederick W., Nussenzweig, André, Potter, Michael, Casellas, Rafael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526190/
https://www.ncbi.nlm.nih.gov/pubmed/18678733
http://dx.doi.org/10.1084/jem.20081007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526190/
https://www.ncbi.nlm.nih.gov/pubmed/18678733
http://dx.doi.org/10.1084/jem.20081007

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