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Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
The cytokine interleukin (IL)-1β is a key mediator of the inflammatory response and has been implicated in the pathophysiology of acute and chronic inflammation. IL-1β is synthesized in response to many stimuli as an inactive pro–IL-1β precursor protein that is further processed by caspase-1 into ma...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526192/ https://www.ncbi.nlm.nih.gov/pubmed/18725521 http://dx.doi.org/10.1084/jem.20071632 |