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Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8

The cytokine interleukin (IL)-1β is a key mediator of the inflammatory response and has been implicated in the pathophysiology of acute and chronic inflammation. IL-1β is synthesized in response to many stimuli as an inactive pro–IL-1β precursor protein that is further processed by caspase-1 into ma...

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Detalles Bibliográficos
Autores principales:	Maelfait, Jonathan, Vercammen, Elisabeth, Janssens, Sophie, Schotte, Peter, Haegman, Mira, Magez, Stefan, Beyaert, Rudi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526192/ https://www.ncbi.nlm.nih.gov/pubmed/18725521 http://dx.doi.org/10.1084/jem.20071632

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