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Dicer-dependent microRNA pathway safeguards regulatory T cell function

Regulatory T (T reg) cells are indispensable for preventing autoimmunity. Incumbent to this role is the ability of T reg cells to exert their suppressor function under inflammatory conditions. We found that T reg cell–mediated tolerance is critically dependent on the Dicer-controlled microRNA (miRNA...

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Detalles Bibliográficos
Autores principales: Liston, Adrian, Lu, Li-Fan, O'Carroll, Donal, Tarakhovsky, Alexander, Rudensky, Alexander Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526195/
https://www.ncbi.nlm.nih.gov/pubmed/18725526
http://dx.doi.org/10.1084/jem.20081062

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