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Dicer-dependent microRNA pathway safeguards regulatory T cell function
Regulatory T (T reg) cells are indispensable for preventing autoimmunity. Incumbent to this role is the ability of T reg cells to exert their suppressor function under inflammatory conditions. We found that T reg cell–mediated tolerance is critically dependent on the Dicer-controlled microRNA (miRNA...
Autores principales: | Liston, Adrian, Lu, Li-Fan, O'Carroll, Donal, Tarakhovsky, Alexander, Rudensky, Alexander Y. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526195/ https://www.ncbi.nlm.nih.gov/pubmed/18725526 http://dx.doi.org/10.1084/jem.20081062 |
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