The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

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MicroRNAs (miRNAs) are implicated in the differentiation and function of many cell types. We provide genetic and in vivo evidence that the two RNaseIII enzymes, Drosha and Dicer, do indeed function in the same pathway. These have previously been shown to mediate the stepwise maturation of miRNAs (Le...

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Detalles Bibliográficos
Autores principales: Chong, Mark M.W., Rasmussen, Jeffrey P., Rudensky, Alexander Y., Littman, Dan R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526196/
https://www.ncbi.nlm.nih.gov/pubmed/18725527
http://dx.doi.org/10.1084/jem.20081219

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