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The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
The nuclear factor of activated T cells (NFAT) family of transcription factors controls calcium signaling in T lymphocytes. In this study, we have identified a crucial regulatory role of the transcription factor NFATc2 in T cell–dependent experimental colitis. Similar to ulcerative colitis in humans...
Autores principales: | Weigmann, Benno, Lehr, Hans A., Yancopoulos, George, Valenzuela, David, Murphy, Andrew, Stevens, Sean, Schmidt, Jan, Galle, Peter R., Rose-John, Stefan, Neurath, Markus F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526204/ https://www.ncbi.nlm.nih.gov/pubmed/18710929 http://dx.doi.org/10.1084/jem.20072484 |
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