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Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
The inflamed liver in chronic hepatitis B virus (HBV) infection (CHB) is characterized by a large influx of non–virus-specific CD8 T cells. Little is known about the functional capacity of these lymphocytes, which could provide insights into mechanisms of failure of viral control and liver damage in...
Autores principales: | Das, Abhishek, Hoare, Matthew, Davies, Nathan, Lopes, A. Ross, Dunn, Claire, Kennedy, Patrick T.F., Alexander, Graeme, Finney, Helene, Lawson, Alistair, Plunkett, Fiona J., Bertoletti, Antonio, Akbar, Arne N., Maini, Mala K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526205/ https://www.ncbi.nlm.nih.gov/pubmed/18695005 http://dx.doi.org/10.1084/jem.20072076 |
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