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Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus

Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolu...

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Autores principales: Kim, Hai Jin, Cho, Min Ho, Park, Jong Suk, Nam, Ji Sun, Kang, Eun Seok, Ahn, Chul Woo, Cha, Bong Soo, Lee, Eun Jig, Lim, Sung Kil, Kim, Kyung Rae, Lee, Hyun Chul, Huh, Kap Bum
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526434/
https://www.ncbi.nlm.nih.gov/pubmed/18437009
http://dx.doi.org/10.3346/jkms.2008.23.2.256
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author Kim, Hai Jin
Cho, Min Ho
Park, Jong Suk
Nam, Ji Sun
Kang, Eun Seok
Ahn, Chul Woo
Cha, Bong Soo
Lee, Eun Jig
Lim, Sung Kil
Kim, Kyung Rae
Lee, Hyun Chul
Huh, Kap Bum
author_facet Kim, Hai Jin
Cho, Min Ho
Park, Jong Suk
Nam, Ji Sun
Kang, Eun Seok
Ahn, Chul Woo
Cha, Bong Soo
Lee, Eun Jig
Lim, Sung Kil
Kim, Kyung Rae
Lee, Hyun Chul
Huh, Kap Bum
author_sort Kim, Hai Jin
collection PubMed
description Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolutional ultrasonography and insulin resistance by Kitt. Half of the cohort had a fatty liver (50.2%). High visceral fat thickness had the highest odds ratio for developing fatty liver in both sexes (odds ratio [S.D]: 3.14 [2.24-4.69], p<0.00 in male, 2.84 [2.04-3.93], p<0.00 in female). In addition, visceral fat thickness of 42.45 and 37.7 mm in men and women, respectively, were chosen as the discriminating value to predict the presence of fatty liver with a sensitivity of 71% and 73% and a specificity of 70% and 70% in men and women, respectively. The area under the receiver-operating characteristics curve was 0.759 in men and 0.764 in women. Therefore we could conclude that the degree of visceral adiposity predicts the presence of fatty liver type 2 diabetes mellitus, whether centrally obese or not, suggesting that hepatic fat accumulation in a diabetic fatty liver may be influenced by visceral fat accumulation regardless of waist circumference.
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spelling pubmed-25264342008-11-06 Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus Kim, Hai Jin Cho, Min Ho Park, Jong Suk Nam, Ji Sun Kang, Eun Seok Ahn, Chul Woo Cha, Bong Soo Lee, Eun Jig Lim, Sung Kil Kim, Kyung Rae Lee, Hyun Chul Huh, Kap Bum J Korean Med Sci Original Article Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolutional ultrasonography and insulin resistance by Kitt. Half of the cohort had a fatty liver (50.2%). High visceral fat thickness had the highest odds ratio for developing fatty liver in both sexes (odds ratio [S.D]: 3.14 [2.24-4.69], p<0.00 in male, 2.84 [2.04-3.93], p<0.00 in female). In addition, visceral fat thickness of 42.45 and 37.7 mm in men and women, respectively, were chosen as the discriminating value to predict the presence of fatty liver with a sensitivity of 71% and 73% and a specificity of 70% and 70% in men and women, respectively. The area under the receiver-operating characteristics curve was 0.759 in men and 0.764 in women. Therefore we could conclude that the degree of visceral adiposity predicts the presence of fatty liver type 2 diabetes mellitus, whether centrally obese or not, suggesting that hepatic fat accumulation in a diabetic fatty liver may be influenced by visceral fat accumulation regardless of waist circumference. The Korean Academy of Medical Sciences 2008-04 2008-04-20 /pmc/articles/PMC2526434/ /pubmed/18437009 http://dx.doi.org/10.3346/jkms.2008.23.2.256 Text en Copyright © 2008 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Hai Jin
Cho, Min Ho
Park, Jong Suk
Nam, Ji Sun
Kang, Eun Seok
Ahn, Chul Woo
Cha, Bong Soo
Lee, Eun Jig
Lim, Sung Kil
Kim, Kyung Rae
Lee, Hyun Chul
Huh, Kap Bum
Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
title Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
title_full Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
title_fullStr Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
title_full_unstemmed Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
title_short Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus
title_sort visceral fat thickness predicts fatty liver in koreans with type 2 diabetes mellitus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526434/
https://www.ncbi.nlm.nih.gov/pubmed/18437009
http://dx.doi.org/10.3346/jkms.2008.23.2.256
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