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Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study
The purpose of this study was to evaluate the outcomes of various methods of multifetal pregnancy reduction (MFPR) and to determine which method produces better outcomes. One hundred and forty-eight patients with multiple pregnancies resulting from assisted reproduction programs and underwent MFPR w...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526504/ https://www.ncbi.nlm.nih.gov/pubmed/18303209 http://dx.doi.org/10.3346/jkms.2008.23.1.111 |
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author | Lee, Jung Ryeol Ku, Seung-Yup Jee, Byung Chul Suh, Chang Suk Kim, Ki Chul Kim, Seok Hyun |
author_facet | Lee, Jung Ryeol Ku, Seung-Yup Jee, Byung Chul Suh, Chang Suk Kim, Ki Chul Kim, Seok Hyun |
author_sort | Lee, Jung Ryeol |
collection | PubMed |
description | The purpose of this study was to evaluate the outcomes of various methods of multifetal pregnancy reduction (MFPR) and to determine which method produces better outcomes. One hundred and forty-eight patients with multiple pregnancies resulting from assisted reproduction programs and underwent MFPR were included. According to the use of potassium chloride (KCl), patients were divided into 'KCl', and 'non-KCl' groups, and based on gestational age at the time of procedures, patients were divided into 'Early' (before 8 weeks of gestation) and 'Late' (at 8 weeks or later) groups. Firstly, to clarify the effect of each component of MFPR procedure, data were analyzed between 'KCl' and 'non-KCl' groups, and between 'Early' and 'Late' groups with adjustments. Secondly, comparison between 'Early, non-KCl' and 'Late, KCl' groups was performed to evaluate the combinative effect of both components. Non-KCl groups showed a significantly higher take-home-baby rate, and lower risk of extreme prematurity and preterm premature rupture of membranes (PPROM) than KCl groups. Early groups showed a lower immediate loss rate than Late groups. As compared with 'Late, KCl' group, 'Early, non-KCl' group was superior in terms of immediate loss, pregnancy loss, take-home-baby, and PPROM rates. Our data suggest that the 'early, non-KCl' method may be a better option for MFPR. |
format | Text |
id | pubmed-2526504 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-25265042008-11-06 Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study Lee, Jung Ryeol Ku, Seung-Yup Jee, Byung Chul Suh, Chang Suk Kim, Ki Chul Kim, Seok Hyun J Korean Med Sci Original Article The purpose of this study was to evaluate the outcomes of various methods of multifetal pregnancy reduction (MFPR) and to determine which method produces better outcomes. One hundred and forty-eight patients with multiple pregnancies resulting from assisted reproduction programs and underwent MFPR were included. According to the use of potassium chloride (KCl), patients were divided into 'KCl', and 'non-KCl' groups, and based on gestational age at the time of procedures, patients were divided into 'Early' (before 8 weeks of gestation) and 'Late' (at 8 weeks or later) groups. Firstly, to clarify the effect of each component of MFPR procedure, data were analyzed between 'KCl' and 'non-KCl' groups, and between 'Early' and 'Late' groups with adjustments. Secondly, comparison between 'Early, non-KCl' and 'Late, KCl' groups was performed to evaluate the combinative effect of both components. Non-KCl groups showed a significantly higher take-home-baby rate, and lower risk of extreme prematurity and preterm premature rupture of membranes (PPROM) than KCl groups. Early groups showed a lower immediate loss rate than Late groups. As compared with 'Late, KCl' group, 'Early, non-KCl' group was superior in terms of immediate loss, pregnancy loss, take-home-baby, and PPROM rates. Our data suggest that the 'early, non-KCl' method may be a better option for MFPR. The Korean Academy of Medical Sciences 2008-02 2008-02-20 /pmc/articles/PMC2526504/ /pubmed/18303209 http://dx.doi.org/10.3346/jkms.2008.23.1.111 Text en Copyright © 2008 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lee, Jung Ryeol Ku, Seung-Yup Jee, Byung Chul Suh, Chang Suk Kim, Ki Chul Kim, Seok Hyun Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study |
title | Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study |
title_full | Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study |
title_fullStr | Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study |
title_full_unstemmed | Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study |
title_short | Pregnancy Outcomes of Different Methods for Multifetal Pregnancy Reduction: A Comparative Study |
title_sort | pregnancy outcomes of different methods for multifetal pregnancy reduction: a comparative study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526504/ https://www.ncbi.nlm.nih.gov/pubmed/18303209 http://dx.doi.org/10.3346/jkms.2008.23.1.111 |
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