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Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral

Although numerous studies have validated the efficacy of intracoronary shunt on reducing left ventricular dysfunction during off-pump coronary artery bypass surgery (OPCAB), there is lack of evidence supporting its role on right ventricular (RV) function during right coronary artery (RCA) revascular...

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Autores principales: Shim, Jae-Kwang, Bang, Sou-Ouk, Lee, Jong-Hwa, Oh, Young-Jun, Yoo, Kyung-Jong, Kwak, Young-Lan
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526513/
https://www.ncbi.nlm.nih.gov/pubmed/18583869
http://dx.doi.org/10.3346/jkms.2008.23.3.373
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author Shim, Jae-Kwang
Bang, Sou-Ouk
Lee, Jong-Hwa
Oh, Young-Jun
Yoo, Kyung-Jong
Kwak, Young-Lan
author_facet Shim, Jae-Kwang
Bang, Sou-Ouk
Lee, Jong-Hwa
Oh, Young-Jun
Yoo, Kyung-Jong
Kwak, Young-Lan
author_sort Shim, Jae-Kwang
collection PubMed
description Although numerous studies have validated the efficacy of intracoronary shunt on reducing left ventricular dysfunction during off-pump coronary artery bypass surgery (OPCAB), there is lack of evidence supporting its role on right ventricular (RV) function during right coronary artery (RCA) revascularization. Therefore, we studied the effect of intracoronary shunt during grafting of dominant RCA without visible collateral supply on global RV function using thermodilution method. Forty patients scheduled for multivessel OPCAB with right dominant coronary circulation without collateral supply confirmed by angiography were randomized to RCA revascularization either with a shunt (n=20) or soft snare occlusion (n=20). RV ejection fraction (RVEF) was recorded at baseline, during RCA grafting, and 15 min after reperfusion. Corresponding RV stroke work index (RVSWI) was calculated. RVEF and RVSWI decreased significantly during RCA grafting and returned to baseline values after reperfusion in both groups without any significant differences between the groups. Intracoronary shunt did not exert any beneficial effect on global RV function during RCA grafting, even in the absence of visible collateral supply. Regarding the possibility of graft failure by intracoronary shunt-induced endothelial damage, routine use of intracoronary shunt during RCA grafting is not recommended in patients with preserved biventricular function.
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spelling pubmed-25265132008-11-07 Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral Shim, Jae-Kwang Bang, Sou-Ouk Lee, Jong-Hwa Oh, Young-Jun Yoo, Kyung-Jong Kwak, Young-Lan J Korean Med Sci Original Article Although numerous studies have validated the efficacy of intracoronary shunt on reducing left ventricular dysfunction during off-pump coronary artery bypass surgery (OPCAB), there is lack of evidence supporting its role on right ventricular (RV) function during right coronary artery (RCA) revascularization. Therefore, we studied the effect of intracoronary shunt during grafting of dominant RCA without visible collateral supply on global RV function using thermodilution method. Forty patients scheduled for multivessel OPCAB with right dominant coronary circulation without collateral supply confirmed by angiography were randomized to RCA revascularization either with a shunt (n=20) or soft snare occlusion (n=20). RV ejection fraction (RVEF) was recorded at baseline, during RCA grafting, and 15 min after reperfusion. Corresponding RV stroke work index (RVSWI) was calculated. RVEF and RVSWI decreased significantly during RCA grafting and returned to baseline values after reperfusion in both groups without any significant differences between the groups. Intracoronary shunt did not exert any beneficial effect on global RV function during RCA grafting, even in the absence of visible collateral supply. Regarding the possibility of graft failure by intracoronary shunt-induced endothelial damage, routine use of intracoronary shunt during RCA grafting is not recommended in patients with preserved biventricular function. The Korean Academy of Medical Sciences 2008-06 2008-06-20 /pmc/articles/PMC2526513/ /pubmed/18583869 http://dx.doi.org/10.3346/jkms.2008.23.3.373 Text en Copyright © 2008 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Shim, Jae-Kwang
Bang, Sou-Ouk
Lee, Jong-Hwa
Oh, Young-Jun
Yoo, Kyung-Jong
Kwak, Young-Lan
Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral
title Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral
title_full Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral
title_fullStr Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral
title_full_unstemmed Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral
title_short Effect of Intracoronary Shunt on Right Ventricular Function During Off-pump Grafting of Dominant Right Coronary Artery with Poor Collateral
title_sort effect of intracoronary shunt on right ventricular function during off-pump grafting of dominant right coronary artery with poor collateral
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526513/
https://www.ncbi.nlm.nih.gov/pubmed/18583869
http://dx.doi.org/10.3346/jkms.2008.23.3.373
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