siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells

The c-Myc and human telomerase reverse transcriptase gene (hTERT) gene are frequently deregulated and overexpressed in malignancy. hTERT activity is induced by c-Myc and strategies designed to inhibit c-Myc expression in cancer cells may have considerable therapeutic value. We designed and used a sh...

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Detalles Bibliográficos
Autores principales: Hao, Huang, Nancai, Yu, Lei, Fu, Xiong, Wei, Wen, Su, Guofu, Huang, yanxia, Wu, Hanju, Huang, Qian, Liu, Hong, Xiao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526986/
https://www.ncbi.nlm.nih.gov/pubmed/18694522
http://dx.doi.org/10.1186/1756-9966-27-27

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