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A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores
BACKGROUND: Safer and more effective mixtures of anticancer drugs are needed, and modeling can assist in this endeavor. This paper describes classification models that were constructed to predict which fixed-ratio mixtures created from a pool of 10 drugs would show a high degree of in-vitro synergis...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526994/ https://www.ncbi.nlm.nih.gov/pubmed/18664274 http://dx.doi.org/10.1186/1471-2210-8-13 |