Key Interactions in Integrin Ectodomain Responsible for Global Conformational Change Detected by Elastic Network Normal-Mode Analysis

Integrin, a membrane protein with a huge extracellular domain, participates in cell-cell and cell-extracellular-matrix interactions for metazoan. A group of integrins is known to perform a large-scale structural change when the protein is activated, but the activation mechanism and generality of the...

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Detalles Bibliográficos
Autores principales: Matsumoto, Atsushi, Kamata, Tetsuji, Takagi, Junichi, Iwasaki, Kenji, Yura, Kei
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2008
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527288/
https://www.ncbi.nlm.nih.gov/pubmed/18515366
http://dx.doi.org/10.1529/biophysj.108.131045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527288/
https://www.ncbi.nlm.nih.gov/pubmed/18515366
http://dx.doi.org/10.1529/biophysj.108.131045

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