Lentivirus Display: Stable Expression of Human Antibodies on the Surface of Human Cells and Virus Particles

BACKGROUND: Isolation of human antibodies using current display technologies can be limited by constraints on protein expression, folding and post-translational modifications. Here we describe a discovery platform that utilizes self-inactivating (SIN) lentiviral vectors for the surface display of hi...

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Detalles Bibliográficos
Autores principales: Taube, Ran, Zhu, Quan, Xu, Chen, Diaz-Griffero, Felipe, Sui, Jianhua, Kamau, Erick, Dwyer, Markryan, Aird, Daniel, Marasco, Wayne A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527531/
https://www.ncbi.nlm.nih.gov/pubmed/18784843
http://dx.doi.org/10.1371/journal.pone.0003181

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