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Paraneoplastic pemphigus regression after thymoma resection

BACKGROUND: Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. CASE PRESENTATION: A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved...

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Autores principales: Barbetakis, Nikolaos, Samanidis, Georgios, Paliouras, Dimitrios, Boukovinas, Ioannis, Asteriou, Christos, Stergiou, Eleni, Laschos, Kostas, Tsilikas, Christodoulos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527607/
https://www.ncbi.nlm.nih.gov/pubmed/18699992
http://dx.doi.org/10.1186/1477-7819-6-83
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author Barbetakis, Nikolaos
Samanidis, Georgios
Paliouras, Dimitrios
Boukovinas, Ioannis
Asteriou, Christos
Stergiou, Eleni
Laschos, Kostas
Tsilikas, Christodoulos
author_facet Barbetakis, Nikolaos
Samanidis, Georgios
Paliouras, Dimitrios
Boukovinas, Ioannis
Asteriou, Christos
Stergiou, Eleni
Laschos, Kostas
Tsilikas, Christodoulos
author_sort Barbetakis, Nikolaos
collection PubMed
description BACKGROUND: Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. CASE PRESENTATION: A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved pemphigus regression. The clinical correlations between pemphigus and thymoma are presented. CONCLUSION: Our case report provides further evidence for the important role of autoantibodies in the pathogenesis of paraneoplastic skin diseases in thymoma patients. It also documents the improvement of the associated pemphigus after radical treatment of the thymoma.
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spelling pubmed-25276072008-09-02 Paraneoplastic pemphigus regression after thymoma resection Barbetakis, Nikolaos Samanidis, Georgios Paliouras, Dimitrios Boukovinas, Ioannis Asteriou, Christos Stergiou, Eleni Laschos, Kostas Tsilikas, Christodoulos World J Surg Oncol Case Report BACKGROUND: Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. CASE PRESENTATION: A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved pemphigus regression. The clinical correlations between pemphigus and thymoma are presented. CONCLUSION: Our case report provides further evidence for the important role of autoantibodies in the pathogenesis of paraneoplastic skin diseases in thymoma patients. It also documents the improvement of the associated pemphigus after radical treatment of the thymoma. BioMed Central 2008-08-12 /pmc/articles/PMC2527607/ /pubmed/18699992 http://dx.doi.org/10.1186/1477-7819-6-83 Text en Copyright © 2008 Barbetakis et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Barbetakis, Nikolaos
Samanidis, Georgios
Paliouras, Dimitrios
Boukovinas, Ioannis
Asteriou, Christos
Stergiou, Eleni
Laschos, Kostas
Tsilikas, Christodoulos
Paraneoplastic pemphigus regression after thymoma resection
title Paraneoplastic pemphigus regression after thymoma resection
title_full Paraneoplastic pemphigus regression after thymoma resection
title_fullStr Paraneoplastic pemphigus regression after thymoma resection
title_full_unstemmed Paraneoplastic pemphigus regression after thymoma resection
title_short Paraneoplastic pemphigus regression after thymoma resection
title_sort paraneoplastic pemphigus regression after thymoma resection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527607/
https://www.ncbi.nlm.nih.gov/pubmed/18699992
http://dx.doi.org/10.1186/1477-7819-6-83
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