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Paraneoplastic pemphigus regression after thymoma resection
BACKGROUND: Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. CASE PRESENTATION: A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527607/ https://www.ncbi.nlm.nih.gov/pubmed/18699992 http://dx.doi.org/10.1186/1477-7819-6-83 |
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author | Barbetakis, Nikolaos Samanidis, Georgios Paliouras, Dimitrios Boukovinas, Ioannis Asteriou, Christos Stergiou, Eleni Laschos, Kostas Tsilikas, Christodoulos |
author_facet | Barbetakis, Nikolaos Samanidis, Georgios Paliouras, Dimitrios Boukovinas, Ioannis Asteriou, Christos Stergiou, Eleni Laschos, Kostas Tsilikas, Christodoulos |
author_sort | Barbetakis, Nikolaos |
collection | PubMed |
description | BACKGROUND: Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. CASE PRESENTATION: A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved pemphigus regression. The clinical correlations between pemphigus and thymoma are presented. CONCLUSION: Our case report provides further evidence for the important role of autoantibodies in the pathogenesis of paraneoplastic skin diseases in thymoma patients. It also documents the improvement of the associated pemphigus after radical treatment of the thymoma. |
format | Text |
id | pubmed-2527607 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25276072008-09-02 Paraneoplastic pemphigus regression after thymoma resection Barbetakis, Nikolaos Samanidis, Georgios Paliouras, Dimitrios Boukovinas, Ioannis Asteriou, Christos Stergiou, Eleni Laschos, Kostas Tsilikas, Christodoulos World J Surg Oncol Case Report BACKGROUND: Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. CASE PRESENTATION: A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported. Transsternal complete thymoma resection achieved pemphigus regression. The clinical correlations between pemphigus and thymoma are presented. CONCLUSION: Our case report provides further evidence for the important role of autoantibodies in the pathogenesis of paraneoplastic skin diseases in thymoma patients. It also documents the improvement of the associated pemphigus after radical treatment of the thymoma. BioMed Central 2008-08-12 /pmc/articles/PMC2527607/ /pubmed/18699992 http://dx.doi.org/10.1186/1477-7819-6-83 Text en Copyright © 2008 Barbetakis et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Barbetakis, Nikolaos Samanidis, Georgios Paliouras, Dimitrios Boukovinas, Ioannis Asteriou, Christos Stergiou, Eleni Laschos, Kostas Tsilikas, Christodoulos Paraneoplastic pemphigus regression after thymoma resection |
title | Paraneoplastic pemphigus regression after thymoma resection |
title_full | Paraneoplastic pemphigus regression after thymoma resection |
title_fullStr | Paraneoplastic pemphigus regression after thymoma resection |
title_full_unstemmed | Paraneoplastic pemphigus regression after thymoma resection |
title_short | Paraneoplastic pemphigus regression after thymoma resection |
title_sort | paraneoplastic pemphigus regression after thymoma resection |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527607/ https://www.ncbi.nlm.nih.gov/pubmed/18699992 http://dx.doi.org/10.1186/1477-7819-6-83 |
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