Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo

Abl interactor (Abi) 1 was first identified as the downstream target of Abl tyrosine kinases and was found to be dysregulated in leukemic cells expressing oncogenic Bcr-Abl and v-Abl. Although the accumulating evidence supports a role of Abi1 in actin cytoskeleton remodeling and growth factor/recept...

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Detalles Bibliográficos
Autores principales: Yu, Weidong, Sun, Xiaolin, Clough, Nancy, Cobos, Everardo, Tao, Yunxia, Dai, Zonghan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527646/
https://www.ncbi.nlm.nih.gov/pubmed/18453543
http://dx.doi.org/10.1093/carcin/bgn098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527646/
https://www.ncbi.nlm.nih.gov/pubmed/18453543
http://dx.doi.org/10.1093/carcin/bgn098

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