Modeling Spinal Muscular Atrophy in Drosophila

Spinal Muscular Atrophy (SMA), a recessive hereditary neurodegenerative disease in humans, has been linked to mutations in the survival motor neuron (SMN) gene. SMA patients display early onset lethality coupled with motor neuron loss and skeletal muscle atrophy. We used Drosophila, which encodes a...

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Detalles Bibliográficos
Autores principales: Chang, Howard Chia-Hao, Dimlich, Douglas N., Yokokura, Takakazu, Mukherjee, Ashim, Kankel, Mark W., Sen, Anindya, Sridhar, Vasanthi, Fulga, Tudor A., Hart, Anne C., Van Vactor, David, Artavanis-Tsakonas, Spyros
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527655/
https://www.ncbi.nlm.nih.gov/pubmed/18791638
http://dx.doi.org/10.1371/journal.pone.0003209

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